Department of Haematology

We invite applications for a Postdoctoral Research Associate to join the lab of Professor Bertie Gottgens at the Cambridge Stem Cell Institute and the Department of Haematology, located on the Cambridge Biomedical Campus.

The successful candidate will become part of a dynamic and collaborative research team with an annual output of ~20 publications (https://www.stemcells.cam.ac.uk/people/pi/gottgens). With 15 years of experience in single-cell genomics, the Gottgens Lab is now focused on integrating large-scale single cell genomics data of early development with cellular dynamics and the molecular programmes that govern individual cell fate decisions. By advancing pioneering statistical and computational approaches, we aim to uncover the principles of cell fate decision-making, sublineage selection, and spatial patterning, and to predict cellular behaviour under genetic or molecular perturbations.

This position is part of a broader research programme investigating the interplay between signalling environments, transcriptional networks, and epigenetic regulators. Our goal is to define the mechanisms that maintain or restrict multipotency and to predict the various modes of cell fate choice. The project will leverage cutting-edge single-cell molecular techniques, spatial profiling, lineage tracing, and genetic perturbation datasets. The successful candidate will lead the computational analysis, integrating epigenetic, transcriptomic, and spatial data to identify the molecular regulatory programmes shaping mouse embryonic development.

https://www.cam.ac.uk/jobs/postdoctoral-research-associate-fixed-term-gottgens-lab-rb47695