Department of Public Health and Primary Care, Cardiovascular Epidemiology Unit
We are looking for a Bioinformatician to work on the Polygenic Score (PGS) Catalog, a collaborative project between the Department of Public Health & Primary Care, EMBL European Bioinformatics Institute, and Health Data Research UK. Since 2019, the PGS Catalog (www.PGSCatalog.org) has been a leading, high-quality data repository for published polygenic scores for a wide range of diseases (e.g. CVD, breast cancer, diabetes) and traits collected through curation and data submitted by authors. The database contains the information necessary for both research and clinical uses of PGS (e.g. SNP information, sample/cohort information, score development details, benchmarking), and is co-developed with the NHGRI-EBI GWAS Catalog (www.ebi.ac.uk/gwas).
The post holder will work directly with our team of expert genetic epidemiologists, biocurators, and a software developer as well as our users and data submitters/authors to deliver the PGS Catalog, a resource with real scientific impact and a variety of clinical applications (data from the Catalog has already been used to return results in clinical trials). The role of the bioinformatician will be to contribute to ongoing PGS Catalog development, software, and data analysis.