Department of Chemical Engineering and Biotechnology

Purpose of the role

Applications are invited for a full time research associate to work within Dr Sebastian Ahnert's group in the Department of Chemical Engineering and Biotechnology. The position involves a close collaboration with the Earlham Institute in Norwich as part of the BBSRC-funded CELLGEN Institute Strategic Programme grant. The project uses computational biology methods to investigate the impact of alternative splicing on protein structure and function.

Key responsibilities

The successful candidate will be conducting computational research in collaboration with Dr Ahnert and researchers at the Earlham Institute. This includes:

• Protein structure prediction using AlphaFold and related approaches.
• Analysis of exon structure in combination with long-read RNA expression data and changes in protein structure and domain structure.
• Exploration of splicing factor and transcription factor regulatory networks in conjunction with long-read RNA expression data and changes in protein structure and domain structure.
• Drive the methodological integration of protein structure prediction methods, exon structure analysis, long-read expression data, and protein domain data.
• Carry out computational biology research both collaboratively and independently
• Produce manuscripts for peer-reviewed journal publications
• Give presentations on the project at internal and external seminars, and conferences and workshops
• Make code and data available as required for publications

• Communicate effectively with collaborators and colleagues

  https://www.cam.ac.uk/jobs/research-assistantresearch-associate-fixed-term-nq50186